This book is designed to furnish Italian literature with an insight into the significance and the role of knowledge transfer, and in particular of technological brokerage. The idea is that, in the present-day world, dominated by a technology and knowledge available to an increasingly large number of people, enterprises are called upon to reconfigure the concept of innovation, expanding in even geographical terms the quest for solutions that aim at creating an exchange of interdisciplinary knowledge. To respond to the need for the dissemination of knowledge, collaboration between enterprises and the use of brokers appears to be the easiest solution. This can contribute to reducing the inefficacy of the markets and hence to facilitating the technological transactions. In this context the role of the brokers is fundamental in the knowledge markets in general, and in particular in that of technology, spawned by the need for an increasingly complex brokerage of knowledge, between applicant and user. In traditional markets, in effect, transactions can be conducted directly by the enterprises and may deal with current or future technology, but there is also the possibility of indirect transactions, involving the intermediation of specialised brokers. The emergence of these brokers is due to the frequent presence of structural gaps in the real markets which do not permit the normal flow of information: in practice, it is rare for every agent in a market to be connected with all the other agents that may important for him.