Sporadic cerebral small vessel disease (SVD) is considered to be among the most commonly known neuropathological processes in the brain, hosting a crucial role in stroke, cognitive impairment, and functional loss in elderly subjects. We investigated clinical (neuroimaging and cognitive) biomarkers in the SVD, through a series of analyses from our five studies. Sporadic cerebral SVD is a complex ‘micro-world’ to be globally considered. All the relevant lesion types and SVD neuroimaging burden should be taken into account. The cumulative effects of microangiopathy burden in the brain of patients affected by SVD are crucial. Cognitive rehabilitation could represent a promising approach to prevent vascular dementia or to improve cognitive performances in patients with cerebral SVD. Longitudinal studies may provide more robust information about the progression and prognostic significance of our findings.
- ORCID: 0000-0002-4975-3754
Book Title
Cerebral Small Vessel Disease and Cerebral Amyloid Angiopathy
Book Subtitle
Neuroimaging markers, cognitive features and rehabilitative issues
Authors
Raffaella Valenti
Peer Reviewed
Number of Pages
182
Publication Year
2018
Copyright Information
© 2018 Author(s)
Content License
Metadata License
Publisher Name
Firenze University Press
DOI
10.36253/978-88-6453-779-5
ISBN Print
978-88-6453-778-8
eISBN (pdf)
978-88-6453-779-5
eISBN (xml)
978-88-9273-086-1
Series Title
Premio Tesi di Dottorato
Series ISSN
2612-8039
Series E-ISSN
2612-8020