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Folding and aggregation studies in the acylphosphatase-like family

  • Francesco Bemporad,

Folding and misfolding of proteins are considered two sides of the same coin. The delicate equilibrium existing between these two processes is crucial for any living organism and its alterations can lead to the onset of several tremendous diseases, such as Alzheimer's and Parkinson's disease. The attainment of a profound knowledge of folding/misfolding processes is a key step to understand how life works and for discovering new therapies to these diseases. In this work the author shows that proteins can display enzymatic activity even in the absence of a compact three-dimensional structure, with important implications for the study of protein enzymes. Furthermore, the author investigates the formation of protein aggregates similar to those observed in patients of amyloid-related diseases.

  • Keywords:
  • Medicina,
  • Biologia,
  • Chimica,
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Francesco Bemporad

University of Florence, Italy - ORCID: 0000-0002-0643-6249

Francesco Bemporad undertook his PhD in Biochemistry in Prof. Fabrizio Chiti's lab at the University of Florence. He obtained the PhD degree in 2008. Currently, he is postdoctoral researcher in Prof. Chris Dobson's lab at the University of Cambridge (UK).
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  • Publication Year: 2009
  • Pages: 126

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  • Publication Year: 2009

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  • Publication Year: 2009
  • Pages: 126

Bibliographic Information

Book Title

Folding and aggregation studies in the acylphosphatase-like family

Authors

Francesco Bemporad

Peer Reviewed

Number of Pages

126

Publication Year

2009

Copyright Information

© 2009 Author(s)

Content License

CC BY-NC-ND 3.0 IT

Metadata License

CC0 1.0

Publisher Name

Firenze University Press

DOI

10.36253/978-88-8453-946-5

ISBN Print

978-88-8453-945-8

eISBN (pdf)

978-88-8453-946-5

eISBN (xml)

978-88-9273-768-6

Series Title

Premio Tesi di Dottorato

Series Issn

2612-8039

Series E-Issn

2612-8020

News and Events
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Premio Tesi di Dottorato - edizione 2009
  • 25/01/2010
  •  | 
  • Aula Magna Università di Firenze – p.zza San Marco 4 Firenze
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