Monograph

Proteins as possible targets for antitumor metal complexes: biophysical studies of their interactions

  • Chiara Gabbiani,

There is considerable interest today for the reactions of anticancer metallodrugs with proteins as these interactions might feature processes that are crucial for the biodistribution, the toxicity and even the mechanism of action of this important group of anticancer agents.
Valuable structural and functional information on these adducts could be derived from several biophysical studies mainly relying on the application of X-ray diffraction and ESI MS techniques. The structural and functional information achieved on the respective metallodrug–protein adducts allowed us to identify some general trends in the reactivity of anticancer metallodrugs with protein targets.

  • Keywords:
  • Biologia,
  • Chimica,
+ Show more
Purchase

Chiara Gabbiani

University of Pisa, Italy - ORCID: 0000-0002-8468-4838

Chiara Gabbiani, BSc in Chemistry (2003), Ph.D in Chemical Sciences (2008), is presently holding a post-doc position in Prof. Messori's research group at the Dept. of Chemistry (University of Florence). Her research interests focus on Inorganic/Medicinal Chemistry, Molecular Biology and Pharmacology.
Table of Contents
PDF
  • Publication Year: 2009
  • Pages: 74
  • eISBN: 978-88-8453-940-3
  • Content License: CC BY-ND 3.0 IT
  • © 2009 Author(s)

XML
  • Publication Year: 2009
  • eISBN: 978-88-9273-767-9
  • Content License: CC BY-ND 3.0 IT
  • © 2009 Author(s)

PRINT
  • Publication Year: 2009
  • Pages: 74
  • eISBN: 978-88-8453-939-7
  • Content License: CC BY-ND 3.0 IT
  • © 2009 Author(s)

Bibliographic Information

Book Title

Proteins as possible targets for antitumor metal complexes: biophysical studies of their interactions

Authors

Chiara Gabbiani

Peer Reviewed

Number of Pages

74

Publication Year

2009

Copyright Information

© 2009 Author(s)

Content License

CC BY-ND 3.0 IT

Metadata License

CC0 1.0

Publisher Name

Firenze University Press

DOI

10.36253/978-88-8453-940-3

ISBN Print

978-88-8453-939-7

eISBN (pdf)

978-88-8453-940-3

eISBN (xml)

978-88-9273-767-9

Series Title

Premio Tesi di Dottorato

Series Issn ISSN

2612-8039

Series E-Issn

2612-8020

303

Fulltext
downloads

337

Views

Search in This Book
Export Citation
Suggested Books

1,188

Open Access Books

in the Catalogue

889

Book Chapters

1,850,327

Fulltext
downloads

2,630

Authors

from 520 Research Institutions

of 51 Nations

51

scientific boards

from 280 Research Institutions

of 39 Nations

785

Referees

from 186 Research Institutions

of 32 Nations