Proteins as possible targets for antitumor metal complexes: biophysical studies of their interactions
- Chiara Gabbiani,
There is considerable interest today for the reactions of anticancer metallodrugs with proteins as these interactions might feature processes that are crucial for the biodistribution, the toxicity and even the mechanism of action of this important group of anticancer agents.
Valuable structural and functional information on these adducts could be derived from several biophysical studies mainly relying on the application of X-ray diffraction and ESI MS techniques. The structural and functional information achieved on the respective metallodrug–protein adducts allowed us to identify some general trends in the reactivity of anticancer metallodrugs with protein targets.
- Keywords:
- Biologia,
- Chimica,
- DOI: 10.36253/978-88-8453-940-3
- Series: Premio Tesi di Dottorato
- Scientific Board
- Language: English
- Subjects: Biology
University of Pisa, Italy - ORCID: 0000-0002-8468-4838
- Publication Year: 2009
- Pages: 74
- eISBN: 978-88-8453-940-3
- Content License: CC BY-ND 3.0 IT
- © 2009 Author(s)
- Publication Year: 2009
- eISBN: 978-88-9273-767-9
- Content License: CC BY-ND 3.0 IT
- © 2009 Author(s)
- Publication Year: 2009
- Pages: 74
- ISBN: 978-88-8453-939-7
- Content License: CC BY-ND 3.0 IT
- © 2009 Author(s)
Bibliographic Information
Book Title
Proteins as possible targets for antitumor metal complexes: biophysical studies of their interactions
Authors
Chiara Gabbiani
Peer Reviewed
Number of Pages
74
Publication Year
2009
Copyright Information
© 2009 Author(s)
Content License
Metadata License
Publisher Name
Firenze University Press
DOI
10.36253/978-88-8453-940-3
ISBN Print
978-88-8453-939-7
eISBN (pdf)
978-88-8453-940-3
eISBN (xml)
978-88-9273-767-9
Series Title
Premio Tesi di Dottorato
Series ISSN
2612-8039
Series E-ISSN
2612-8020
News and Events
Premio Tesi di Dottorato - edizione 2009
- 25/01/2010 |
- Aula Magna Università di Firenze – p.zza San Marco 4 Firenze
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