Molecular imaging in Parkinson's disease
- Cristina Polito,
The present work explores brain functional changes in drug-naïve Parkinson's disease (PD) patients by means of molecular imaging techniques. Thirty-one consecutive drug-naïve PD patients from the Neurological Clinic of the University of Flor-ence underwent clinical assessment, neuropsychological assessment, MRI, [123I]FP-CIT SPECT, [18F]FDG PET.
First, [18F]FDG-PET was employed to identify in drug-naïve PD patients brain metabolic alteration uniquely related to disease process and not modulated by anti-parkinsonian therapeutic intervention. Second, [18F]FDG-PET and [123I]FP-CIT SPECT were employed together to explore the early functional changes in brain function related to dopaminergic depletion in the putamen and in the caudate nucleus.
- DOI: 10.36253/978-88-6655-041-9
- Series: Premio Tesi di Dottorato
- Scientific Board
- Language: English
- Subjects: Medicine
University of Florence, Italy - ORCID: 0000-0001-7509-5575
- Publication Year: 2011
- Pages: 68
- eISBN: 978-88-6655-041-9
- Content License: CC BY-ND 3.0 IT
- © 2011 Author(s)
- Publication Year: 2011
- eISBN: 978-88-9273-645-0
- Content License: CC BY-ND 3.0 IT
- © 2011 Author(s)
- Publication Year: 2011
- Pages: 68
- ISBN: 978-88-6655-037-2
- Content License: CC BY-ND 3.0 IT
- © 2011 Author(s)
Bibliographic Information
Book Title
Molecular imaging in Parkinson's disease
Authors
Cristina Polito
Peer Reviewed
Number of Pages
68
Publication Year
2011
Copyright Information
© 2011 Author(s)
Content License
Metadata License
Publisher Name
Firenze University Press
DOI
10.36253/978-88-6655-041-9
ISBN Print
978-88-6655-037-2
eISBN (pdf)
978-88-6655-041-9
eISBN (xml)
978-88-9273-645-0
Series Title
Premio Tesi di Dottorato
Series ISSN
2612-8039
Series E-ISSN
2612-8020
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